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Updated NICE Sepsis Guideline

NICE have published updated guidance recommending more tailored treatment for patients aged over 16 with suspected Sepsis.

The guidance recommends using smaller amounts of intravenous fluid initially for those at high risk, and reassessing patients after infusion, so that treatment can be tailored.  It also recommends taking extra care assessing people for sepsis who might not have English as their first language, or for people with communication difficulties.

"Our updated guidelines provide useful and useable information to ensure people receive the right treatment in the right clinical setting. We have acted on feedback from stakeholders to ensure that our sepsis guidelines provide the information people need in a readily accessible way."

Professor Jonathan Benger, Deputy Chief Executive and Chief Medical Officer, NICE

NICE has split its sepsis guidance into three separate guidelines covering people aged 16 and over, children and young people, and those who are pregnant or recently pregnant. The change makes it easier for practitioners and the public to quickly find relevant information.  NICE will soon begin work on the next update to the sepsis guidelines, which will focus on reviewing the use of paediatric and maternity national early warning scores. These are tools used to spot when a patient's condition is deteriorating. 

"The clinical tools published by the UK Sepsis Trust have closely reflected NICE guidance over the last decade, and we have been privileged once again to work with the team at NICE to ensure that our tools are as accurate as possible. We welcome these new changes, which reinforce groups of people at particular risk of harm from sepsis including those who communicate differently."

Dr Ron Daniels, Join CEO and Founder, UK Sepsis Trust 

Download the Guidance 

Source www.nice.org.uk 

Hear more at:

Sepsis in Children and Young Adults
Friday 22nd May 2026 | Virtual Conference

This timely conference focuses on early recognition and management of Sepsis in Children and Young Adults and will support you to improve practice and outcomes. The conference will also cover the implementation of Marthas Rule in paediatrics.

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